• Earthquakes, Medical Devices, and You

    Collapsed General Hospital in Mexico City following September 1985 earthquake.Let's face it: Earthquakes are a way of life in California. Just this week, a 4.7-magnitude temblor epicentered east of San Diego rattled windows, flung groceries from supermarket shelves, and jarred nerves.But what does all this have to do with medical devices? For one thing, California represents the largest concentration of medical device research, development, and manufacturing in the United States. In addition,...
  • Stanford Scientists Develop Super Thin, High-Res Endoscope

    Researchers at Stanford have created an endoscope with a diameter roughly as thin as a human hair. Capable of imaging objects 2.5 microns in size, the current prototype boasts a resolution four times greater than previous endoscope designs. In fact, the endoscope can produce four times as many image features than they expected.The next-generation prototype may have a resolution as small as 0.3 microns, generating some 80,000 pixels. By contrast, conventional high-resolution endoscopes can...
  • Metamaterials Next Trick? Making Ultrasound Imaging High-Def

    In 2011, we reported that metamaterials, man-made materials with exotic properties, might be able to boost the resolution of ultrasound imaging by a factor of 50. On a related note, a team of international researchers, including Texas A&M Professor Vladislav Yakovlev pictured on the right, have developed a prototype of the metamaterial-containing transducer that could significantly improve the resolution of ultrasound imaging by converting ultrasound waves into optical rather than...
  • Are Your Power Supplies Meeting the IEC 60601-1 3rd Edition Standard?

    For medical devices, power supplies are required to meet exacting standards as defined in the IEC 60601-1 3rd edition, that were effective as of June of 2012 for Europe. The IEC 60601-1 standard is a globally recognized standard for electro-medical equipment safety. The next evolution in the IEC 60601-1 third edition requires a risk management file and process conforming to ISO 14971, the international standard for application of risk management to medical devices.Medical device OEMs are...
  • Analytical Theory Could Improve Lithium-Ion Batteries

    Purdue researchers have shown theoretically how to control or eliminate dendrite formation in lithium-ion batteries. Dendrites can cause an internal short circuit, resulting in battery failure and possible fire. (Image courtesy of Quinn Horn, Exponent)Lithium-ion (Li-ion) batteries caused quite a stir not long ago by catching fire on the Boeing 787 Dreamliner. But because Li-ion batteries are also used widely in a range of medical devices, concerns go beyond the critical question of airline...
  • How 3-D Printing Is Reinventing Benchtop Testing

    Traditionally, benchtop models, particularly for cardiovascular applications, have been either made of blown glass for rigid parts or silicone for compliant models. Medical device engineers would take the hand-blown pieces of glass or the molded silicone replicas and use it in early product testing. Although the transparency of glass and silicone can be useful, the accuracy of such models is limited and they can be expensive as they are generally made by hand or injection molding.  ...
  • Flexible Batteries Could Be Used to Power Implants

    The era of conformal electronics may be approaching. Two pioneers in the space of flexible electronics have announced the development of a stretchable lithium-ion battery. The battery is compatible with the stretchable electronics they helped develop earlier, which could be worn like temporary tattoos to monitor vital signs as well in a variety of medical device applications. Known as the “Biostamp,” that technology is now being commercialized by MC10 (Cambridge, MA).In Nature Communications,...
  • Is 3-D Technology Headed to the Operating Room?

    In medicine, 2-D imaging had long been the norm—just look at the traditional chest x-ray as but one example of that. Nevertheless, there has been a gradual shift in medicine towards 3-D imaging, which his now used to assess everything from the heart’s vasculature to the colon. In actuality, however, those images, while giving the illusion of three dimensions, are still viewed on a flat monitor.Technology that can accurately impart the sense of three dimensions, both with and without glasses,...
  • Light Marks the Spot on Medical Implants

    A custom, flexible laser marking system marks medical devices, checks quality, and connects to front- and back-office production and inventory systems.Although laser marking may seem a straightforward task when compared, for instance, to developing wrist implants or artificial hips, poor marking systems can introduce pinch points in the manufacturing process or even stop the line entirely in the event of failure.When Wright Medical Technologies (Arlington, TN) went looking for a new production-...
  • Princeton Study Shows Effect of Bacteria on Medical Devices

    Over 40 hours, bac­te­r­ial cells (green) flowed through a chan­nel, form­ing a green biofilm on the walls. Over the next 10 hours, researchers sent red bac­te­r­ial cells through the chan­nel. The red cells became stuck in the biofilm and began to form thin red stream­ers, which trapped addi­tional cells, lead­ing to rapid clog­ging. (Image source: Knut Drescher)A new study from Princeton University (Princeton, NJ) sheds light on how bacteria can clog medical devices. According to results from...
  • MD&M West: Medical Materials Mecca

    The Q-Flo valve connector from Infusion Innovations Inc. is made using Bayer's Makrolon resin.Readers of MPMN’s Medtech Pulse may have noticed that bioresorbable materials took center stage at MD&M West. But there’s much more to the world of medical device materials than the admittedly crucial space occupied by bioresorbables and bioabsorbables. Here’s a small sampling of other types of medical device materials that were on display at the show.Medical-Grade Polycarbonate…and MoreBayer...
  • In 2012, Adverse Events Soar for Polymeric Surgical Meshes

    Vaginal mesh continues to be making headlines lately, joining the ranks of products like metal-on-metal hip implants, which attract scores of lawsuits. Last year, a California jury awarded $5 million to a plaintiff in the first major transvaginal mesh lawsuit, which centered around Bard Medical’s Avaulta mesh. Only today, a New Jersey court handed out $3.35 million in a case related to Ethicon’s Gynecare Prolift mesh. That case was the first of more than 1800 that are pending in New Jersey...
  • New Imaging Modality Offers Nanoscale Resolution

    This image symbolically depicts the nanomanipulation of an artificial atom.A new imaging modality that is similar to MRI but offers a resolution roughly one million fold greater, enabling it to scan individual cells. Developed by scientists at the Institute of Photonic Sciences (ICFO), the CSIC, and Macquarie University in Australia, the technique makes use of artificial atoms and doped diamond nanoparticles to detect extremely weak magnetic fields generated by certain biological molecules....
  • Flexible Imaging Technology Could Be Used in Next-Gen Endoscopes

    A group of Austrian researchers have developed a new imaging method that makes use of a transparent polymer sheet that is flat and flexible. Conversely, the majority of image sensors are rigid, planar, and opaque. In addition, the novel image sensor does not use integrated microstructures such as circuits.The thin-film luminescent concentrator is flexible as well as transparent. The image depicts a Bayer Makrofol LISA Green LC film absorbing blue light and re-emitting it at a green wavelength....
  • Technologies Fueling Faster, Cheaper, and Better Medical Devices

    FutureMed executive director Daniel Kraft, MD giving a keynote at MD&M West. Medical device designers should keep a close eye on exponentially accelerating technologies, recommended FutureMed executive director Daniel Kraft, MD at a keynote address at MD&M West in Anaheim, CA. “Medical devices are starting to integrate many of these technologies as they get faster, cheaper and better and more applicable,” he said. These technologies are also shrinking and coming down in cost, enabling...
  • How the Visible Human Project Was Applied to a Medical Device Application

    In 1989, planning began for creating an atlas of cross-sectional images from a male and female cadaver. Dubbed the “Visible Human Project,” the undertaking was completed by the mid-1990s.At a conference session at MD&M West, BioDigital’s cofounder Aaron Oliker explained how the researchers from the U.S. National Library of Medicine (NLM) obtained the male data. “They took an inmate [who had donated his body to science] and they cryofroze him like Han Solo, sliced him into little pieces,...
  • Revamped Medical Tubing Puller/Cutter Saves Time, Cuts Costs

    Sometimes a minor change can have a major impact. By simply adding an optional air-feed cutter bushing to its established Medline tubing puller/cutter, for example, Conair (Cranberry Township, PA) claims to have dramatically improved process efficiency, ultimately saving customers time and money."We try to feel our customers’ pain and come up with solutions," Bob Bessemer, Conair sales manager, medical extrusion, said yesterday at MD&M West. "[The optional bushing design] looks very simple...
  • One Trillion Frames Per Second: Tapping the Power of Super-High-Speed Imaging

    At FutureMed, professor Ramesh Raskar at MIT’s Media Lab shed light on imaging technology that is so fast that it can be used to create slow-motion video of light in motion. Impressively, the imaging modality also can see around corners. That capability could expand the power of medical applications such as endoscopy, where it could enable the imaging of irregular surfaces within the heart or locate hidden polyps in the colon.The camera works by sending a series of incredibly short laser pulses...
  • Overcoming Engineering Challenges: Developing a Tiny Robotically Steerable Guidewire

    As a company that develops medical products that typically comprise micro-electromechanical systems (MEMS), our greatest engineering challenge is rooted in the sheer physical size of our devices. For example, our flagship product is a robotically steerable interventional guidewire with a diameter of 0.014 in. (0.36mm)—the IntelliWire. Equivalent to just two strands of human hair thick, the core of this device houses an array of electrical and mechanical components, which collectively make up a...
  • Bioresorbable Materials Take Center Stage at MD&M West

    At this year's MD&M West, bioresorbable and bioabsorbable materials were the focus of conference sessions and company product announcements alike. At the MedTech Innovate Seminar session on bioresorbable materials, Dennis D. Jamiolkowski, distinguished research fellow, at Ethicon Inc., Johnson & Johnson Co.; Derek Mortisen, senior scientist at Abbott Laboratories; and Mart Eenink, director, global sales biomaterials at Purac highlighted the chemical and mechanical issues involved with...