Medical Device Coatings

As the world leader in medical device coatings, SurModics technology has been used successfully on over 150 commercial device applications across the following markets: cardiovascular, diabetes, gastrointestinal, neurology, obesity, oncology, ophthalmology, and urology. SurModics is the first choice of medical device manufacturers who seek performance, clinical, regulatory and manufacturing advantages.

SurModics’ coating technologies are utilized by medical device companies for numerous applications.

SurModics' PhotoLink® Coating Technology
The technology behind SurModics' lubricious and hemocompatible hydrophilic coatings is our patented PhotoLink chemistry—which produces a photo-initiated covalent bond to device substrates—the preferred approach to surface modification. The simplicity of the PhotoLink coating process makes it easy to integrate into existing manufacturing processes.

PhotoLink Technology Advantages

• Best-in-class lubricity and durability
• Flexibility to coat a wide variety of materials and devices
• Approved for use on medical devices in US, Europe, China and Japan
• Efficient, high-throughput manufacturing with minimal floor space requirements
• Coated devices can be tested and packaged minutes after coating
• No harsh chemicals and does not produce hazardous byproducts
• Reduced time-to-market

Lubricious Coatings
SurModics lubricious hydrophilic coatings provide best-in-class lubricity and surface durability for many types of medical devices. We can reduce the coefficient of friction on a vast array of materials by up to 95% while preserving the lubricious characteristics under extreme clinical conditions. These lubricious surfaces have also been shown to demonstrate passive hemocompatibility and infection resistance.

Hemocompatible Coatings
SurModics heparin-based coatings help reduce adverse reactions on a variety of blood-contacting medical devices. Our PhotoLink coating process covalently binds heparin to the device surface to shield the blood from the underlying medical device material. The immobilized heparin inhibits blood clotting on the surface, minimizes patient risk, and enhances the performance of the device. SurModics also continues to develop a variety of non-heparin coating options to reduce platelet adhesion and thrombus formation, such as lysine copolymer, fatty acid, and sulfonates.

Drug Delivery Coatings
SurModics biocompatible polymer coatings are widely applicable for augmenting medical device functionality for local drug delivery. This technology is highly tunable, enabling us to produce products that meet your therapeutic dosing and duration requirements (typically ranging from a period of days to months). We can deliver a wide range of compounds (from small molecules to proteins) for a variety of therapeutic or antimicrobial needs. These systems employ durable and biodegradable polymer technologies.

Multifunctional Coatings
One of the strong attributes of SurModics coating technology is its ability to deliver multiple characteristics simultaneously. Medical devices often require multiple surface characteristics to achieve optimum performance. For example, SurModics can customize a coating that is lubricious for improved deliverability and hemocompatible for the reduced likelihood of clotting.

SurModics' Support Services
We provide critical, comprehensive services to our customers throughout the product development cycle, from the feasibility phase to commercialization.

• Compliant to the Quality Management System Standards ISO 9001:2008 and ISO 13485:2003
• World-class analytical and surface characterization capabilities
• Contract coating services and manufacturing support for devices in the pre-clinical and clinical development stages
• Consulting on regulatory pathways and submission assistance (we also maintain device master files with the FDA to help expedite the regulatory path for emerging products.)
• Technology transfer service to help our customers integrate the coating process into existing manufacturing systems and procedures at the customer's facility
• Ongoing technical support, manufacturing support and problem solving, and next generation product development

Contact Us
SurModics has a proven record of bringing products from concept to successful commercialization for large corporations and small emerging companies. At SurModics, we regard our customers as partners and strive to add to your success.
How can we help you? Talk to an expert today (866-787-6639 or 952-500-7000).

For more details on SurModics medical device coating technology, you may download this brochure or visit www.surmodics.com.

In Vitro Diagnostic Products

SurModics also offers innovative diagnostic assay components and technologies for the in vitro diagnostic, biopharmaceutical, and research markets. Considered by many to be the gold standard among competing products in several of our offerings, SurModics is an established leader, celebrating over 30 years of research and development history as a provider of high-quality products and technologies, enabling our customers to create products and systems that are exceptional.

For more information about SurModics In Vitro Diagnostic products you may download our product catalog or visit www.surmodics.com.